What is Homocysteine?
Homocysteine is a sulfur-containing amino acid produced in the body during the metabolism of the essential amino acid methionine, which involves a series of conversions that require enzymes. Homocysteine is a natural substance made by the body, not to be feared, but to be appreciated and controlled. Homocysteine functions at a metabolic crossroad that can affect the methyl and sulfur group metabolism of key enzymes, hormones, and vital nutrients. Many important nutrients, especially B vitamins, are needed for these enzymes.
The Problem with too Much Homocysteine
The circulation of excess homocysteine can damage the lining of arterial walls so they become narrow and inelastic. Research suggests that a raised homocysteine level is an independent risk factor for hardening of the arteries, coronary heart disease, stroke, peripheral vascular disease and other conditions associated with abnormal blood clotting. Elevated homocysteine is also linked with a number of other serious medical conditions, including osteoporosis, Alzheimer’s disease, multiple sclerosis, rheumatoid arthritis, spontaneous abortion, placental abruption, renal failure, and type II diabetes. When homocysteine is elevated it reduces nitric oxide (NO) production via increasing levels of ADMA which can increase the risk of hypertension and erectile dysfunction.
Synergistic nutrients found in MethylPlus facilitate the efficient metabolism of homocysteine, preventing toxic levels of homocysteine from accumulating. This makes it possible for a functioning pathway to provide necessary methyl and sulfur groups for a myriad of biochemical reactions, especially those needed for detoxification, joint and cartilage repair, and brain health.